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by Dr. Markho Rafael

For two millennia, medicinal mushrooms have been mainstream in Asia. Now, America is taking notice and interest is rapidly “mushrooming.” With the sprouting of this new industry follows issues of ethical quality claims between competing brands.

All species of medicinal mushrooms appear haunted by this issue. Particularly so, it seems, is red reishi (Ganoderma lucidum), the oldest medicinal mushroom in Traditional Chinese Medicine. Please note, however, that the information in this article applies generally to all medicinal mushroom species.

An obvious caution is to stay away from cheap, mass-produced reishi. It may be merely dried and pulverized. In order to be medicinal, the mushroom cell-wall has to be broken down. Mass-produced reishi may be mostly inert and ineffective.

There are many real therapeutic brands on the market, though. But even among them, there are significant differences. They all claim to be the best, naturally, because they all want to sell their particular brand. So let’s sift the data, get the facts straight, and clear up misleading information that is out there.

Following are the three primary ways of creating reishi extracts. Each method yields different medicinal compounds, all of which are shown in scientific studies to have important properties.

1. Water (Hot) Extraction (polysaccharides, etc.)

2. Alcohol Extraction (triterpenoids, sterols)

3. Fermented (arabinoxylanes, etc.)

Polysaccharides have been shown to possess powerful anti-tumor qualities through enhancing the immune system and by inhibiting blood profusion through tumors. They are also strong antioxidants. [1]

Triterpenoids include a large number of related medicinal compounds whose proven effects include stabilization of blood pressure, cholesterol, and blood clotting. But most importantly, the triterpenoids are the anti-inflammatory compounds of reishi. [1] Inflammation is a serious component in asthma, allergies, arthritis and many more conditions.

Finally, by fermenting the red reishi, the original medicinal compounds break down to form new compounds with unique healing properties. These “secondary metabolites” have among other things been shown to be immune enhancing and help regulate blood sugar, as well as having unique anti-tumor properties. [2]

Since this article is not intended to elevate any one brand over another, no brand names will be mentioned. Nevertheless, the author does know of two highly reputed brands (American and Japanese) that claim only hot water extracted red reishi is of any value and that alcohol extracts are useless.

Of course they do that to promote their own brand. In reality both hot water extract and alcohol extract contain unique medicinal compounds that are all very important.

To find the best red reishi products, look for those brands that use at least the first two extraction methods in combination: Hot Water Extraction and Alcohol Extraction. Better yet would be brands that incorporate all three extraction methods, including Fermentation.

Last but not least, remember to look at the form the reishi comes in. If the reishi is able to dissolve completely in water-based drinks like coffee, it’s a safe bet that it only contains the water-soluble polysaccharides. An excellent choice as far as coffee goes but an incomplete reishi supplement because it does not include the anti-inflammatory triterpenoid compounds.

Alcohol tinctures, on the other hand, are well worth considering because they may be a blend of water and alcohol extracts. The way to tell is if the tincture is cloudy. When water-soluble polysaccharides get mixed with alcohol, they fall out of solution. Cloudiness in an alcohol tincture indicates high polysaccharide content. Just shake before taking. Tablets and capsules can contain hot water extract, alcohol extract or both. You need to find out from the manufacturer.

[1] Boh B, Berovic M, Zhang J, Zhi-Bin L. “Ganoderma lucidum and its pharmaceutically active compounds.” Biotechnology Annual Review 2007;13:265-301.

[2] Tang YJ, Zhang W, Zhong JJ, 2009. “Performance analyses of a pH-shift and DOT-shift integrated fed-batch fermentation process for the production of ganoderic acid and Ganoderma polysaccharides by medicinal mushroom Ganoderma lucidum.” Bioresource Technol. Mar;100(5):1852-9.

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